Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | QPCT | Q16769 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14669371 | 0.88 | NPC1 (0.53) | MMP12NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL2093317 | 0.87 | MMP12 (0.75) | MMP12NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL225931 | 0.86 | MMP12 (0.73) | MMP12NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL29919790 | 0.86 | MMP12 (0.73) | MMP12NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL2096521 | 0.86 | MMP12 (0.55) | MMP12ALDH1A1QPCTDYRK1AQPCTL | |
| SCHEMBL6008269 | 0.84 | MAPT (0.50) | MMP12NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL31143361 | 0.84 | MAPT (0.50) | MMP12NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL1608484 | 0.81 | MAPT (0.56) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL13373486 | 0.81 | PARP1 (0.46) | MMP12ALDH1A1KDM4EQPCTQPCTL | |
| SCHEMBL14669369 | 0.80 | MMP12 (0.52) | MMP12NPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866543-B | A method of benzimidazole compound is catalyzed and synthesized under microwave radiation in water phase | 福建医科大学 | 2019-05-14 | — | — | CN | disclosed |