Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 13/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28940943 | 0.85 | ANO1 (0.48) | ANO1 | |
| SCHEMBL22341853 | 0.81 | ANO1 (0.50) | ANO1 | |
| SCHEMBL21379443 | 0.80 | ANO1 (0.46) | ANO1POLB | |
| SCHEMBL21379445 | 0.80 | ANO1 (0.46) | ANO1POLB | |
| SCHEMBL23405316 | 0.80 | ANO1 (0.47) | ANO1KMT2AKITBRAF | |
| SCHEMBL13852609 | 0.80 | KMT2A (0.52) | POLBKMT2ACNR1 | |
| SCHEMBL6613121 | 0.80 | MAP2K1 (0.44) | POLBKMT2ABRAFCNR1 | |
| SCHEMBL28663446 | 0.79 | KDM4E (0.55) | ANO1 | |
| SCHEMBL8945334 | 0.78 | POLB (0.54) | POLBKMT2A | |
| SCHEMBL21379406 | 0.77 | NAMPT (0.48) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-109689647-A | The compound that bicyclic heteroaryl replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |