Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL8503458 | 0.93 | CA4 (0.60) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL31501592 | 0.93 | CA4 (0.60) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL28476051 | 0.93 | CA4 (0.60) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL50463 | 0.93 | — | — | |
| Methacrylic Acid SCHEMBL672152 | 0.93 | CA4 (0.53) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL4818992 | 0.93 | CA4 (0.60) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL6049028 | 0.90 | CA4 (0.50) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL6837203 | 0.90 | CA4 (0.50) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL10800152 | 0.90 | CA4 (0.50) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL1572161 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109610192-A | A kind of tear-proof polypropylene-base synthetic leather material and preparation method thereof | 郑永江 | 2019-04-12 | — | — | CN | disclosed |