Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 4/20 | 0.60 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.57 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL28476051 | 1.00 | CA4 (0.60) | CA4CA1FAHD1TDP1MEN1 | |
| Methacrylic Acid SCHEMBL50463 | 1.00 | — | — | |
| Methacrylic Acid SCHEMBL31501592 | 1.00 | CA4 (0.60) | CA4CA1FAHD1TDP1MEN1 | |
| Methacrylic Acid SCHEMBL8503458 | 1.00 | CA4 (0.60) | CA4CA1FAHD1TDP1MEN1 | |
| Methacrylic Acid SCHEMBL27853461 | 0.96 | — | — | |
| Methacrylic Acid SCHEMBL27891307 | 0.96 | — | — | |
| Methacrylic Acid SCHEMBL1572161 | 0.96 | — | — | |
| Methacrylic Acid SCHEMBL27783004 | 0.96 | CA4 (0.56) | CA4CA1FAHD1TDP1MEN1 | |
| Methacrylic Acid SCHEMBL19384595 | 0.96 | CA4 (0.57) | CA4CA1FAHD1TDP1MEN1 | |
| Methacrylic Acid SCHEMBL59390 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3263355-B1 | PLANOGRAPHIC PRINTING PLATE PRECURSOR, PLATE-MAKING METHOD FOR PLANOGRAPHIC PRINTING PLATE, AND PRINTING METHOD | FUJIFILM CORP (JP) | 2020-03-25 | — | — | EP | disclosed |
| US-20180009212-A1 | PLANOGRAPHIC PRINTING PLATE PRECURSOR, PLATE-MAKING METHOD FOR PLANOGRAPHIC PRINTING PLATE, AND PRINTING METHOD | FUJIFILM CORPORATION (JP) | 2018-01-11 | — | — | US | disclosed |
| EP-3263355-A1 | ORIGINAL PLATE OF PLANOGRAPHIC PRINTING PLATE, PLATE-MAKING METHOD FOR PLANOGRAPHIC PRINTING PLATE, AND PRINTING METHOD | FUJIFILM Corporation (JP) | 2018-01-03 | — | — | EP | disclosed |
| US-7405179-B2 | Thermosensitive recording medium and method of manufacturing the same | TOSHIBA TEC KABUSHIKI KAISHA (JP) | 2008-07-29 | — | — | US | disclosed |
| EP-1577110-B1 | Thermosensitive recording medium and method of manufacturing the same | TOSHIBA TEC KK (JP) | 2007-01-03 | — | — | EP | disclosed |
| EP-1710090-A1 | Thermosensitive recording medium and method of manufacturing the same | Toshiba Tec Kabushiki Kaisha (JP) | 2006-10-11 | — | — | EP | disclosed |
| US-7115721-B2 | Microorganism, its product and utilization thereof | ASTELLAS PHARMA INC. (JP) | 2006-10-03 | — | — | US | disclosed |
| CN-1715072-A | Thermosensitive recording medium and manufacturing method thereof | TOSHIBA TEC KK (JP) | 2006-01-04 | — | — | CN | disclosed |
| CN-1715071-A | Method of manufacturing thermosensitive recording medium | TOSHIBA TEC KK (JP) | 2006-01-04 | — | — | CN | disclosed |
| US-20050255996-A1 | Thermosensitive recording medium and manufacturing method thereof | TOSHIBA TEC KABUSHIKI KAISHA (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1595715-A2 | Method of manufacturing thermosensitive recording medium | Toshiba Tec Kabushiki Kaisha (JP) | 2005-11-16 | — | — | EP | disclosed |
| EP-1595716-A2 | Thermosensitive recording medium and manufacturing method thereof | Toshiba Tec Kabushiki Kaisha (JP) | 2005-11-16 | — | — | EP | disclosed |
| US-20050215431-A1 | Thermosensitive recording medium and method of manufacturing the same | TOSHIBA TEC KABUSHIKI KAISHA (JP) | 2005-09-29 | — | — | US | disclosed |
| EP-1577110-A1 | Thermosensitive recording medium and method of manufacturing the same | Toshiba Tec Kabushiki Kaisha (JP) | 2005-09-21 | — | — | EP | disclosed |
| US-20050063927-A1 | Novel microorganism, its product and utilization thereof | ASTELLAS PHARMA INC. (JP) | 2005-03-24 | — | — | US | disclosed |
| EP-1469080-A1 | NOVEL MICROORGANISM, ITS PRODUCT AND UTILIZATION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2004-10-20 | — | — | EP | disclosed |
| EP-0622245-B1 | Thermal recording material | JUJO PAPER CO LTD (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0838345-A1 | Thermal recording material | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1998-04-29 | — | — | EP | disclosed |
| US-5494882-A | CONTAINING A DITHIOUREA COMPOUND | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0622245-A1 | Thermal recording material | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1994-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050063927-A1 | Novel microorganism, its product and utilization thereof | TYR, ALPG, INCENP | CA4 1071/4885CA1 4007/4885FAHD1 4240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.