Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 3/20 | 0.50 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.47 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PEPD | P12955 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL6049028 | 1.00 | CA4 (0.50) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL10800152 | 1.00 | CA4 (0.50) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL3224823 | 0.94 | CA4 (0.44) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL28118231 | 0.94 | CA4 (0.44) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL3210511 | 0.91 | CA4 (0.42) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL28292650 | 0.90 | CA4 (0.53) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL11359770 | 0.90 | CA1 (0.50) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL8503458 | 0.90 | CA4 (0.60) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL4818992 | 0.90 | CA4 (0.60) | CA4CA1FAHD1TDP1FFAR3 | |
| Methacrylic Acid SCHEMBL50463 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10299995-B2 | Method for producing hydrogel particles | KAO CORPORATION (JP) | 2019-05-28 | — | — | US | disclosed |
| US-20180168940-A1 | METHOD FOR PRODUCING HYDROGEL PARTICLES | KAO CORPORATION (JP) | 2018-06-21 | — | — | US | disclosed |
| US-20040114013-A1 | Inkjet ink and inkjet recording method | FUJI XEROX CO., LTD. | 2004-06-17 | — | — | US | disclosed |