Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL28384964 | 0.96 | — | — | |
| Methacrylic Acid SCHEMBL8503459 | 0.96 | TDP1 (0.50) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL264345 | 0.96 | — | — | |
| Methacrylic Acid SCHEMBL59948 | 0.96 | TDP1 (0.50) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL1723751 | 0.96 | TDP1 (0.50) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL25392450 | 0.92 | — | — | |
| Methacrylic Acid SCHEMBL11058354 | 0.92 | TDP1 (0.47) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL3207375 | 0.92 | TDP1 (0.47) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL28476049 | 0.92 | — | — | |
| Methacrylic Acid SCHEMBL27835871 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109610192-A | A kind of tear-proof polypropylene-base synthetic leather material and preparation method thereof | 郑永江 | 2019-04-12 | — | — | CN | disclosed |