Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | LDHB | P07195 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL1723751 | 1.00 | TDP1 (0.50) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL11058354 | 0.96 | TDP1 (0.47) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL11058360 | 0.96 | TDP1 (0.47) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL3207375 | 0.96 | TDP1 (0.47) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL28292654 | 0.96 | TDP1 (0.47) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL15043 | 0.96 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL15005463 | 0.96 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL11235035 | 0.96 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL491341 | 0.96 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL182989 | 0.96 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240198582-A1 | HYBRID RESIN COMPOSITION FOR THE 3D-PRINTING OF OBJECTS | CUBICURE GMBH (AT) | 2024-06-20 | — | — | US | claimed |
| US-11987658-B2 | Curable resin composition and method of manufacturing article | CANON KABUSHIKI KAISHA (JP) | 2024-05-21 | — | — | US | claimed |
| EP-3802695-B1 | STRETCHABLE SOLID-STATE ELECTROACTIVE POLYMER ACTUATORS | BIOASTRA TECH INC (CA) | 2023-07-05 | — | — | EP | claimed |
| US-20220282013-A1 | CURABLE RESIN COMPOSITION AND METHOD OF MANUFACTURING ARTICLE | CANON KABUSHIKI KAISHA (JP) | 2022-09-08 | — | — | US | claimed |
| EP-2669085-B1 | DECORATIVE SHEET, AND DECORATIVE RESIN-MOLDED ARTICLE EMPLOYING SAME | DAINIPPON PRINTING CO LTD (JP) | 2019-08-21 | — | — | EP | claimed |
| US-10273258-B2 | Process for the preparation of acylphosphanes | ETH ZUERICH (CH) | 2019-04-30 | — | — | US | claimed |
| US-10265895-B2 | Decorative sheet for three-dimensional molding and method for producing same, and decorative molded article using decorative sheet and method for producing same | DAI NIPPON PRINTING CO., LTD. (JP) | 2019-04-23 | — | — | US | claimed |
| US-20180002357-A1 | PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH ZUERICH (CH) | 2018-01-04 | — | — | US | claimed |
| EP-2689929-B1 | DECORATIVE SHEET FOR THREE-DIMENSIONAL MOLDING AND METHOD FOR PRODUCING SAME, AND DECORATIVE MOLDED ARTICLE USING DECORATIVE SHEET AND METHOD FOR PRODUCING SAME | DAINIPPON PRINTING CO LTD (JP) | 2017-09-13 | — | — | EP | claimed |
| US-9605120-B2 | Decorative sheet, and decorative resin-molded article employing same | DAI NIPPON PRINTING CO., LTD. (JP) | 2017-03-28 | — | — | US | claimed |
| WO-2007054289-A2 | AQUEOUS POWDER DISPERSION, WHICH CAN BE CURED BY RADICAL POLYMERIZATION, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE | BASF COATINGS AG (DE) | 2007-05-18 | — | — | WO | claimed |
| WO-2007054288-A1 | REPAIR FILM AND USE THEREOF | BASF COATINGS AG (DE) | 2007-05-18 | — | — | WO | claimed |
| WO-2005090494-A1 | CER COMPOUNDS USED AS INITIATORS FOR THERMAL HARDENING | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-29 | — | — | WO | claimed |
| EP-0965620-B1 | Weather resistant carbonate acrylate radiation-curable coating compositions | BASF AG (DE) | 2003-04-23 | — | — | EP | claimed |
| EP-0951496-B1 | ALKYD AND ARALKYD DERIVATIVES OF PHENOLIC POLYMERS | GEORGIA PACIFIC RESINS (US) | 2001-12-19 | — | — | EP | claimed |
| EP-0965620-A1 | Weather resistant carbonate acrylate radiation-curable coating compositions | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-22 | — | — | EP | claimed |
| EP-0424219-B1 | Polycarbonate-polyol composition and polycarbonate (meth) acrylate compositions and urethane (meth) acrylate compositions prepared therefrom | DAICEL CHEM (JP) | 1996-05-08 | — | — | EP | claimed |
| US-5143997-A | Photo-curable or electron-beam curable coatings | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-01 | — | — | US | claimed |
| EP-0424219-A2 | Polycarbonate-polyol composition and polycarbonate (meth) acrylate compositions and urethane (meth) acrylate compositions prepared therefrom | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1991-04-24 | — | — | EP | claimed |
| EP-0106110-A1 | Process for preparing copolymers of monoethylenically unsaturated mono- and dicarboxylic acids | BASF Aktiengesellschaft (DE) | 1984-04-25 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10273258-B2 | Process for the preparation of acylphosphanes | AGPAT5, AGPAT2, PHOSPHO1 | TDP1 3637/4885FFAR3 2651/4885LCK 2615/4885 |
| US-20180002357-A1 | PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | AGPAT5, AGPAT2, PHOSPHO1 | TDP1 3637/4885FFAR3 2651/4885LCK 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.