Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851747 | 0.87 | TLR2 (0.72) | TLR2MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL19851664 | 0.87 | TLR2 (0.72) | TLR2MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL19851534 | 0.87 | TLR2 (0.57) | TLR2MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL28291266 | 0.85 | TLR2 (0.72) | TLR2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL28292695 | 0.85 | TLR2 (0.51) | TLR2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL19839686 | 0.85 | MEN1 (0.55) | TLR2MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL19839673 | 0.85 | MEN1 (0.55) | TLR2MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL19839675 | 0.85 | MEN1 (0.55) | TLR2MEN1KMT2AMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL28291264 | 0.84 | TLR2 (0.70) | TLR2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL19851861 | 0.82 | TLR2 (0.69) | TLR2MEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715167-A | Lipid-substituted amino 1, 2-and 1, 3-diol compounds as modulators of TLR2 dimerization | 神经孔疗法股份有限公司 | 2019-05-03 | — | — | CN | claimed |