Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | NOS3 | P29474 | 1/20 | 0.61 |
| ▸ | NOS1 | P29475 | 1/20 | 0.61 |
| ▸ | NOS2 | P35228 | 1/20 | 0.61 |
| ▸ | PI4KA | P42356 | 1/20 | 0.61 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.61 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.61 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.61 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Aminopyridine SCHEMBL5693366 | 0.88 | NOS3 (0.73) | L3MBTL1CYP3A4MAPTTSHRBLM | |
| Benzoic Acid SCHEMBL28858300 | 0.87 | NOS3 (0.59) | L3MBTL1POLBCYP3A4PARP1MAPT | |
| 2-Aminopyridine SCHEMBL29007661 | 0.86 | DHODH (0.56) | L3MBTL1POLBCYP3A4PARP1MAPT | |
| 2-Aminopyridine SCHEMBL2152741 | 0.86 | NOS3 (0.76) | L3MBTL1NOS3NOS1NOS2PI4KA | |
| 2-Aminopyridine SCHEMBL28327874 | 0.86 | NOS3 (0.76) | L3MBTL1POLBBLMNOS3NOS1 | |
| Niacinamide SCHEMBL28217395 | 0.84 | F7 (0.71) | L3MBTL1MAPTNOS3NOS1NOS2 | |
| Dipyridyl SCHEMBL15380517 | 0.84 | TDP1 (0.67) | L3MBTL1POLBCYP3A4PARP1MAPT | |
| 2-Aminopyridine SCHEMBL15953718 | 0.84 | NOS3 (0.67) | L3MBTL1NOS3NOS1NOS2PI4KA | |
| 2-Aminopyridine SCHEMBL27257074 | 0.84 | NOS3 (0.73) | L3MBTL1NOS3NOS1NOS2PI4KA | |
| 2-Aminopyridine SCHEMBL27257075 | 0.84 | NOS3 (0.73) | L3MBTL1NOS3NOS1NOS2PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748929-A | A kind of preparation method of compound | 苏州鹏旭医药科技有限公司 | 2019-05-14 | — | — | CN | disclosed |