Niacinamide

Niacinamide

SCHEMBL28217395

NC(=O)c1cccnc1.Nc1ccccn1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.71
F3 P13726 1/20 0.71
SARM1 Q6SZW1 1/20 0.71
SIRT2 Q8IXJ6 1/20 0.71
SIRT6 Q8N6T7 1/20 0.71
SIRT1 Q96EB6 1/20 0.71
SIRT3 Q9NTG7 1/20 0.71
SIRT5 Q9NXA8 1/20 0.71
SIRT4 Q9Y6E7 1/20 0.71
NOS3 P29474 1/20 0.52
NOS1 P29475 1/20 0.52
NOS2 P35228 1/20 0.52
PI4KA P42356 1/20 0.52
PI4K2B Q8TCG2 1/20 0.52
PI4K2A Q9BTU6 1/20 0.52
PI4KB Q9UBF8 1/20 0.52
NNMT P40261 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
F2 P00734 1/20 0.49
F12 P00748 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Niacinamide SCHEMBL7753606 0.86 F7 (0.96) F7F3SARM1SIRT2SIRT6
Benzamide SCHEMBL28292769 0.84 L3MBTL1 (0.61) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL27671762 0.84 F7 (0.92) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL2926 0.84
Niacinamide SCHEMBL19978192 0.84
Niacinamide SCHEMBL29624874 0.84
Niacinamide SCHEMBL460466 0.84 F7 (1.00) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL9065096 0.84 F7 (0.71) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL2745101 0.83 F7 (0.88) F7F3SARM1SIRT2SIRT6
Benzamide SCHEMBL594793 0.83 F7 (0.88) F7F3SARM1SIRT2SIRT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105618078-B A kind of catalyst for ammoxidation alkyl pyridine 沧州临港亚诺化工有限公司 2018-05-22 CN disclosed