Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28028802 | 0.82 | TAAR1 (0.55) | GAAALDH1A1HPGDEPHX1 | |
| SCHEMBL8621389 | 0.79 | GAA (0.55) | GAABCHEALDH1A1KMT2AHPGD | |
| SCHEMBL1720194 | 0.79 | ALDH1A1 (0.67) | GAABCHEALDH1A1KMT2AHPGD | |
| SCHEMBL1415939 | 0.78 | PLAU (0.52) | GAABCHEALDH1A1KMT2AHPGD | |
| SCHEMBL2095021 | 0.77 | GAA (0.53) | GAABCHEALDH1A1KMT2AHPGD | |
| SCHEMBL29244564 | 0.77 | GAA (0.53) | GAABCHEALDH1A1KMT2AHPGD | |
| SCHEMBL28058232 | 0.77 | BCHE (0.55) | GAABCHEALDH1A1KMT2AHPGD | |
| SCHEMBL1129046 | 0.77 | CYP2D6 (0.56) | GAABCHEALDH1A1KMT2AHPGD | |
| SCHEMBL21201600 | 0.77 | GAA (0.53) | GAABCHEALDH1A1KMT2AHPGD | |
| SCHEMBL17552096 | 0.76 | NPC1 (0.69) | GAAALDH1A1KMT2AHPGDEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104350055-B | Bicyclic heteroaryl derivatives and application thereof as MNK1 and MNK2 regulator | 新加坡科技研究局 | 2019-05-31 | — | — | CN | disclosed |