SCHEMBL28292848

SCHEMBL28292848

NC(=O)NNC(N)=S.Nc1nc(N)nc(N)n1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CA1 P00915 2/20 0.42
CA9 Q16790 2/20 0.42
CYP1A2 P05177 1/20 0.37
RRM2 P31350 2/20 0.36
GAA P10253 5/20 0.35
CRHBP P24387 1/20 0.34
HTT P42858 1/20 0.34
CRHR2 Q13324 1/20 0.34
MCOLN3 Q8TDD5 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
IDO1 P14902 1/20 0.33
LMNA P02545 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL653171 0.82
Lithium Ion SCHEMBL28340040 0.76 ALDH1A1 (0.62) ALDH1A1HPGDHSD17B10CA1CA9
Water SCHEMBL28179339 0.76 ALDH1A1 (0.62) ALDH1A1HPGDHSD17B10CA1CA9
SCHEMBL517626 0.74 ALDH1A1 (0.39) ALDH1A1CA1CA9CYP1A2GAA
Thiourea SCHEMBL5852257 0.73 TSHR (0.46) CYP1A2SMN1; SMN2LMNAATM
Bicarbonate SCHEMBL4615338 0.73 CYP1A2 (0.57) ALDH1A1HPGDHSD17B10CA1CA9
Urea SCHEMBL15483993 0.73 CYP1A2 (0.50) ALDH1A1HPGDCYP1A2GAASMN1; SMN2
Urea SCHEMBL10914180 0.73 CYP1A2 (0.50) ALDH1A1HPGDCYP1A2GAASMN1; SMN2
Bicarbonate SCHEMBL5708571 0.73 CYP1A2 (0.57) ALDH1A1HPGDHSD17B10CA1CA9
Urea SCHEMBL51851 0.73 CYP1A2 (0.50) ALDH1A1HPGDCYP1A2GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109632697-A A kind of method of illegal additive in quick identification baby formula milk powder 广东出入境检验检疫局检验检疫技术中心 2019-04-16 CN disclosed