Thiourea

Thiourea

SCHEMBL5852257

NC(N)=S.Nc1nc(N)nc(N)n1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
ATM Q13315 1/20 0.46
ATR Q13535 1/20 0.46
LMNA P02545 1/20 0.41
CASP1 P29466 1/20 0.38
CYP1A2 P05177 1/20 0.38
ADORA2A P29274 3/20 0.33
ADORA1 P30542 2/20 0.33
POLB P06746 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA2B P29275 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPC1 O15118 2/20 0.31
RAB9A P51151 1/20 0.31
PDPK1 O15530 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxyamine SCHEMBL8577072 0.79 LMNA (0.47) LMNACASP1CYP1A2ADORA2AADORA1
Hydrogen Peroxide SCHEMBL6095945 0.79 CYP1A2 (0.50) TSHRLMNACASP1CYP1A2ADORA2A
SCHEMBL29485005 0.78
SCHEMBL29900242 0.78
SCHEMBL29876207 0.78
SCHEMBL25853 0.78
SCHEMBL8465809 0.78 CASP1 (0.50) LMNACASP1CYP1A2ADORA2AADORA1
SCHEMBL175612 0.78 CASP1 (0.50) LMNACASP1CYP1A2ADORA2AADORA1
SCHEMBL9583239 0.78 CASP1 (0.50) LMNACASP1CYP1A2ADORA2AADORA1
SCHEMBL9579151 0.78 CASP1 (0.50) LMNACASP1CYP1A2ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1293135-C Composites comprising fibers dispersed in polymer matrix having improved shielding PARK HANNIFIN CORP (US) 2007-01-03 CN disclosed
US-7078098-B1 Composites comprising fibers dispersed in a polymer matrix having improved shielding with lower amounts of conducive fiber PARKER-HANNIFIN CORPORATION (US) 2006-07-18 US disclosed
CN-1440440-A Composites comprising fibers dispersed in polymer matrix having improved shielding PARK HANNIFIN CORP (US) 2003-09-03 CN disclosed
EP-1297064-A2 COMPOSITES COMPRISING FIBERS DISPERSED IN A POLYMER MATRIX HAVING IMPROVED SHIELDING Parker Hannifin Corporation (US) 2003-04-02 EP disclosed
WO-2002002686-A2 COMPOSITES COMPRISING FIBERS DISPERSED IN A POLYMER MATRIX HAVING IMPROVED SHIELDING PARKER HANNIFIN CORPORATION (US) 2002-01-10 WO disclosed
US-5171419-A Cobalt tungsten or nickel tungsten alloy AMERICAN CYANAMID COMPANY (US) 1992-12-15 US disclosed
US-4983456-A Compositions convertible to reinforced conductive components and articles incorporating same AMERICAN CYANAMID 1991-01-08 US disclosed
US-4882089-A Compositions convertible to reinforced conductive components and articles incorporating same AMERICAN CYANAMID COMPANY (US) 1989-11-21 US disclosed
US-4808481-A CORE WITH ELECTRICALLY CONDUCTIVE AND THERMOPLASTIC ADHESIVE LAYERS; COMPOSITES AMERICAN CYANAMID COMPANY (US) 1989-02-28 US disclosed
US-4783243-A Articles comprising metal-coated polymeric substrates and process AMERICAN CYANAMID COMPANY (US) 1988-11-08 US disclosed
US-4239725-A CATIONICALLY POLYMERIZABLE IN THE PRESENCE OF A CATALYST OF A DIARYL IODONIUM SALT, A COPPER SALT AND A REDUCING AGENT GENERAL ELECTRIC COMPANY (US) 1980-12-16 US disclosed
US-4238587-A DIARYLIODONIUM SALT, COPPER CHELATE GENERAL ELECTRIC COMPANY (US) 1980-12-09 US disclosed
US-4230814-A USING DIALKYL HYDROXYARYLSULFONIUM SALTS WITH AN ORGANIC OXIDANT GENERAL ELECTRIC COMPANY 1980-10-28 US disclosed
US-4225691-A DIARYLDIIODONIUM SALTS GENERAL ELECTRIC COMPANY (US) 1980-09-30 US disclosed
WO-1980001695-A1 CURABLE ORGANIC RESIN COMPOSITIONS AND FOAMING METHOD GEN ELECTRIC (US) 1980-08-21 WO disclosed
WO-1980001723-A1 HEAT CURABLE COMPOSITIONS GEN ELECTRIC (US) 1980-08-21 WO disclosed
US-4216288-A Heat curable cationically polymerizable compositions and method of curing same with onium salts and reducing agents GENERAL ELECTRIC COMPANY (US) 1980-08-05 US disclosed
US-4192924-A DIARYLIOPONIUM SALT REDOX CATALYST GENERAL ELECTRIC COMPANY (US) 1980-03-11 US disclosed
US-4173551-A ARYLIODONIUM SALT, COPPER SALT OR ACID OR ANHYDRIDE CATIONIC CATALYST GENERAL ELECTRIC COMPANY (US) 1979-11-06 US disclosed
US-4102687-A UREA, PHENOLIC OR MELAMINE RESIN; SULFUR, SELENIUM, TELLURIUM PHOTOINITIATOR GENERAL ELECTRIC COMPANY (US) 1978-07-25 US disclosed