Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 16/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 16/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294469 | 0.85 | PDGFRB (0.51) | PDGFRBPDGFRACA12CA1CA2 | |
| SCHEMBL28294470 | 0.80 | PDGFRB (0.47) | PDGFRBPDGFRACA12CA1CA2 | |
| SCHEMBL29213981 | 0.76 | MET (0.41) | PDGFRBPDGFRACA12CA1CA2 | |
| SCHEMBL26549500 | 0.74 | CA12 (0.57) | PDGFRBPDGFRACA12CA1CA2 | |
| SCHEMBL15161581 | 0.74 | PDGFRB (0.41) | PDGFRBPDGFRACA12CA1CA2 | |
| SCHEMBL12294158 | 0.73 | CA2 (0.37) | CA1CA2 | |
| SCHEMBL12275709 | 0.73 | CA2 (0.37) | CA1CA2 | |
| SCHEMBL7602494 | 0.73 | PDGFRB (0.48) | PDGFRBPDGFRACA12CA1CA2 | |
| SCHEMBL20193401 | 0.72 | EPAS1 (0.37) | CA1CA2 | |
| SCHEMBL19877811 | 0.72 | PDE4A (0.37) | PDGFRBPDGFRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851554-B | Method for preparing trifluoromethanesulfonic acid-6-quinoline ester derivative | 中国科学院大连化学物理研究所 | 2022-05-17 | — | — | CN | disclosed |
| CN-109851554-A | A method of preparing trifluoromethanesulfonic acid -6- quinoline ester derivant | 中国科学院大连化学物理研究所 | 2019-06-07 | — | — | CN | disclosed |