Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294651 | 0.85 | PSMB5 (0.45) | PSMB5KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL28569921 | 0.81 | CYP3A4 (0.42) | KDM4EALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL15723539 | 0.80 | TDP1 (0.46) | KDM4EALDH1A1NPSR1LMNATDP1 | |
| SCHEMBL28905343 | 0.80 | NPC1 (0.42) | ALDH1A1KMT2AMAPTTDP1CYP3A4 | |
| SCHEMBL29669786 | 0.79 | TDP1 (0.41) | MEN1KMT2ALMNATDP1CYP3A4 | |
| SCHEMBL28133194 | 0.79 | LMNA (0.42) | PSMB5ALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL12592439 | 0.79 | TDP1 (0.44) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28535167 | 0.78 | ALDH1A1 (0.40) | KDM4EALDH1A1LMNAMAPTTDP1 | |
| SCHEMBL28510500 | 0.78 | CYP1A2 (0.40) | KDM4EALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL28530516 | 0.78 | CYP3A4 (0.39) | ALDH1A1MAPTRECQLTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478627-B | Allylated monophosphine ligand and preparation method thereof | 湖北大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-113666961-B | Preparation method of meta-substituted biaryl tertiary phosphine ligand | 湖北大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-112876507-B | Trisubstituted olefin tertiary phosphine compound and preparation method thereof | 湖北大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114478627-A | Allylation monophosphine ligand and preparation method thereof | 湖北大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-113666961-A | Preparation method of meta-substituted biaryl tertiary phosphine ligand | 湖北大学 | 2021-11-19 | — | — | CN | disclosed |
| CN-112876507-A | Trisubstituted olefin tertiary phosphine compound and preparation method thereof | 湖北大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-109851635-B | Novel alkylated monophosphine ligand and simple preparation method thereof | 湖北大学 | 2021-03-16 | — | — | CN | disclosed |
| CN-112250709-A | Synthesis method of ortho-aryl substituted tertiary phosphine compound | 湖北大学 | 2021-01-22 | — | — | CN | disclosed |
| CN-109851635-A | A kind of new alkylation monophosphorus ligand and its simple preparation method | 湖北大学 | 2019-06-07 | — | — | CN | disclosed |