Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720145 | 0.85 | ADRB2 (0.77) | ADRB2KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL6242472 | 0.84 | ADRB3 (0.57) | ADRB3ADRB1 | |
| SCHEMBL28808178 | 0.84 | ADRB2 (0.67) | ADRB2KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL27635389 | 0.77 | GAA (0.63) | KDM4EGAATDP1ALDH1A1 | |
| SCHEMBL4467885 | 0.76 | ADRB2 (0.73) | ADRB2KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL9543386 | 0.76 | ADRB2 (0.73) | ADRB2KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL4467889 | 0.76 | ADRB2 (0.73) | ADRB2KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL10731026 | 0.75 | KDM4E (0.63) | ADRB2KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL10731030 | 0.75 | KDM4E (0.63) | ADRB2KDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL9061577 | 0.75 | KDM4E (0.63) | ADRB2KDM4EL3MBTL1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734712-A | The pyrrolidine derivative and application thereof that aryl or heteroaryl replace | 广东东阳光药业有限公司 | 2019-05-10 | — | — | CN | disclosed |