Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 5/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293101 | 0.87 | HINT1 (0.42) | HINT1HPRT1MEN1KMT2AMAPK1 | |
| SCHEMBL28294847 | 0.80 | HINT1 (0.41) | HINT1MEN1KMT2AHBBNT5E | |
| SCHEMBL25387706 | 0.74 | HPGD (0.40) | HINT1HPRT1MEN1KMT2AHBB | |
| SCHEMBL26130922 | 0.72 | HINT1 (0.41) | HINT1MEN1KMT2AHBBNT5E | |
| SCHEMBL27875028 | 0.71 | ADORA3 (0.45) | HINT1MEN1KMT2AHBBNT5E | |
| SCHEMBL28293060 | 0.71 | ADORA3 (0.42) | HINT1MEN1KMT2AHBBNT5E | |
| SCHEMBL30206547 | 0.70 | HINT1 (0.34) | HINT1HPRT1MEN1KMT2AMAPK1 | |
| SCHEMBL28293053 | 0.70 | — | — | |
| SCHEMBL7063505 | 0.69 | HINT1 (0.38) | HINT1HBBNT5EBLM | |
| SCHEMBL1514934 | 0.68 | PNP (0.36) | HINT1HPRT1MEN1KMT2AHBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661232-A | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | 纽约哥伦比亚大学董事会 | 2019-04-19 | — | — | CN | disclosed |