Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | FDPS | P14324 | 1/20 | 0.67 |
| ▸ | PEPD | P12955 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | MVD | P53602 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL8405467 | 0.97 | BLM (0.71) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL28233480 | 0.93 | BLM (0.67) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL28175198 | 0.93 | BLM (0.67) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL4016977 | 0.93 | BLM (0.77) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL8060467 | 0.90 | BLM (0.71) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL28305758 | 0.87 | BLM (0.67) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL27905890 | 0.86 | FDPS (0.77) | BLMTDP1FDPSCA4CA2 | |
| Pyrophosphoric Acid SCHEMBL29053870 | 0.86 | FDPS (0.77) | BLMTDP1FDPSCA4CA2 | |
| Pyrophosphoric Acid SCHEMBL621307 | 0.86 | FDPS (0.91) | BLMTDP1FDPSCA4CA2 | |
| Pyrophosphoric Acid SCHEMBL8879584 | 0.86 | FDPS (0.91) | BLMTDP1FDPSCA4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109640947-A | Intranasal pharmaceutical powder compositions | 株式会社新日本科学 | 2019-04-16 | — | — | CN | disclosed |