Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | FDPS | P14324 | 1/20 | 0.77 |
| ▸ | PEPD | P12955 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MVD | P53602 | 3/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL8405467 | 0.96 | BLM (0.71) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL8060467 | 0.96 | BLM (0.71) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL28175198 | 0.93 | BLM (0.67) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL28293071 | 0.93 | BLM (0.67) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL28233480 | 0.93 | BLM (0.67) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL28305758 | 0.93 | BLM (0.67) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL1680134 | 0.92 | FDPS (0.91) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL4420910 | 0.88 | FDPS (0.83) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL8811725 | 0.88 | FDPS (0.83) | BLMTDP1FDPSPEPDCA4 | |
| Pyrophosphoric Acid SCHEMBL27618497 | 0.88 | FDPS (0.83) | BLMTDP1FDPSPEPDCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430081-A | Fire retardant additive and fire retardant thermoplastic resin composition | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1995-07-04 | — | — | US | claimed |
| US-5122556-A | Plasticized polycarbonates; tensile strength; elastic modulus; thin-walled precision injection-molded housings for electronic equipment | GENERAL ELECTRIC COMPANY (US) | 1992-06-16 | — | — | US | claimed |
| CN-111254139-A | Method for extracting total RNA and total protein of matrix microorganisms under strong acid condition | 南京大学 | 2020-06-09 | — | — | CN | disclosed |
| EP-3130578-B1 | FERTILIZING COMPOSITION WHICH INCLUDES AN INHIBITOR OF UREASE ACTIVITY | FERTINAGRO BIOTECH SL (ES) | 2019-03-13 | — | — | EP | disclosed |
| EP-3130578-A1 | FERTILIZING COMPOSITION WHICH INCLUDES AN INHIBITOR OF UREASE ACTIVITY | Fertinagro Nutrientes, S.L. (ES) | 2017-02-15 | — | — | EP | disclosed |
| CN-103054901-A | Dialysates and methods and systems related thereto | UNIV EMORY | 2013-04-24 | — | — | CN | disclosed |
| EP-1682077-A4 | DIALYSATES AND METHODS AND SYSTEMS RELATED THERETO | UNIV EMORY (US) | 2009-07-01 | — | — | EP | disclosed |
| CN-101094681-A | Dialysate and related methods and systems | UNIV EMORY (US) | 2007-12-26 | — | — | CN | disclosed |
| US-20070148258-A1 | Dialysates and methods and systems related thereto | EMORY UNIVERSITY | 2007-06-28 | — | — | US | disclosed |
| EP-1682077-A2 | DIALYSATES AND METHODS AND SYSTEMS RELATED THERETO | Emory University (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005044189-A2 | DIALYSATES AND METHODS AND SYSTEMS RELATED THERETO | EMORY UNIVERSITY (US) | 2005-05-19 | — | — | WO | disclosed |
| US-5430081-A | Fire retardant additive and fire retardant thermoplastic resin composition | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| US-5122556-A | Plasticized polycarbonates; tensile strength; elastic modulus; thin-walled precision injection-molded housings for electronic equipment | GENERAL ELECTRIC COMPANY (US) | 1992-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070148258-A1 | Dialysates and methods and systems related thereto | SOST, REN, DDO | BLM 2950/4885TDP1 2221/4885FDPS 2542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.