Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28644147 | 0.86 | GABRA1 (0.44) | GABRA1GABRB1GABRA3GABRB2MAPK1 | |
| SCHEMBL29003940 | 0.85 | ALDH1A1 (0.56) | MAPK1ALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL27518983 | 0.84 | ALDH1A1 (0.56) | MAPK1HSD17B10ALDH1A1KDM4ETSHR | |
| SCHEMBL21113639 | 0.82 | ALDH1A1 (0.46) | GABRA1GABRB1GABRA3GABRB2MAPK1 | |
| SCHEMBL11287118 | 0.82 | TSHR (0.58) | MAPK1HSD17B10ALDH1A1KDM4ETSHR | |
| SCHEMBL26981616 | 0.81 | TSHR (0.53) | MAPK1HSD17B10ALDH1A1GAAKMT2A | |
| Ammonia Solution, Strong SCHEMBL8815847 | 0.80 | TSHR (0.52) | MAPK1HSD17B10ALDH1A1KDM4EGAA | |
| SCHEMBL28291324 | 0.79 | ALDH1A1 (0.60) | MAPK1HSD17B10ALDH1A1KDM4ETSHR | |
| SCHEMBL27647669 | 0.79 | ALDH1A1 (0.60) | MAPK1HSD17B10ALDH1A1KDM4ETSHR | |
| SCHEMBL28134121 | 0.79 | TSHR (0.49) | GABRA1GABRB1GABRA3GABRB2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109762117-A | The synthetic method of polyether polyol | 山东蓝星东大有限公司 | 2019-05-17 | — | — | CN | disclosed |