SCHEMBL28293173

SCHEMBL28293173

Oc1ccc(-c2ccc(O)c(-c3ccccc3)c2)cc1-c1ccccc1.Oc1ccc(-c2ccc(O)c(-c3ccccc3)c2)cc1-c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.71
HSD17B1 P14061 1/20 0.67
HSD17B2 P37059 1/20 0.67
ALOX5 P09917 2/20 0.62
ALDH1A1 P00352 2/20 0.61
HPGD P15428 2/20 0.61
HSD17B10 Q99714 2/20 0.61
BCL2L1 Q07817 2/20 0.61
ESR2 Q92731 2/20 0.56
KDM4E B2RXH2 1/20 0.56
MEN1 O00255 1/20 0.56
USP2 O75604 1/20 0.56
LMNA P02545 1/20 0.56
HSP90AA1 P07900 1/20 0.56
GAA P10253 1/20 0.56
MAPT P10636 1/20 0.56
ALOX15 P16050 1/20 0.56
ALOX12 P18054 1/20 0.56
HTT P42858 1/20 0.56
KMT2A Q03164 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL344800 1.00 BACE1 (0.71) BACE1HSD17B1HSD17B2ALOX5ALDH1A1
SCHEMBL29485605 1.00 BACE1 (0.71) BACE1HSD17B1HSD17B2ALOX5ALDH1A1
SCHEMBL509310 0.98 BACE1 (0.68) BACE1HSD17B1HSD17B2ALOX5ALDH1A1
SCHEMBL332052 0.98 BACE1 (0.68) BACE1HSD17B1HSD17B2ALOX5ALDH1A1
SCHEMBL10046081 0.98 BACE1 (0.68) BACE1HSD17B1HSD17B2ALOX5ALDH1A1
SCHEMBL9541038 0.95 BACE1 (0.65) BACE1HSD17B1HSD17B2ALOX5ALDH1A1
SCHEMBL16581370 0.95 HSD17B1 (0.68) BACE1HSD17B1HSD17B2ALOX5ALDH1A1
SCHEMBL25427059 0.93 BACE1 (0.62) BACE1HSD17B1HSD17B2ALOX5ALDH1A1
SCHEMBL510164 0.91 BCL2L1 (0.62) BACE1HSD17B1HSD17B2ALOX5ALDH1A1
SCHEMBL510289 0.91 BCL2L1 (0.62) BACE1HSD17B1HSD17B2ALOX5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790274-A URETHANE RESIN USING POLYROTAXANE, AND POLISHING PAD 株式会社德山 2019-05-21 CN disclosed