SCHEMBL510164

SCHEMBL510164

Oc1ccc(-c2ccc(-c3ccc(O)c(-c4ccccc4)c3)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 2/20 0.62
MMP3 P08254 1/20 0.62
BACE1 P56817 1/20 0.60
ALOX5 P09917 3/20 0.59
HSD17B1 P14061 2/20 0.59
HSD17B2 P37059 2/20 0.59
ESR1 P03372 4/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
ESR2 Q92731 4/20 0.54
USP7 Q93009 1/20 0.54
ALDH1A1 P00352 2/20 0.53
HPGD P15428 2/20 0.53
HSD17B10 Q99714 2/20 0.53
KDM4E B2RXH2 1/20 0.53
USP2 O75604 1/20 0.53
LMNA P02545 1/20 0.53
HSP90AA1 P07900 1/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL510289 1.00 BCL2L1 (0.62) BCL2L1MMP3BACE1ALOX5HSD17B1
SCHEMBL509310 0.94 BACE1 (0.68) BCL2L1MMP3BACE1ALOX5HSD17B1
SCHEMBL332052 0.94 BACE1 (0.68) BCL2L1MMP3BACE1ALOX5HSD17B1
SCHEMBL10046081 0.94 BACE1 (0.68) BCL2L1MMP3BACE1ALOX5HSD17B1
SCHEMBL27831348 0.92 ALOX5 (0.59) BCL2L1MMP3BACE1ALOX5HSD17B1
SCHEMBL16393890 0.91 ALOX5 (0.65) ALOX5HSD17B1HSD17B2ESR1MEN1
SCHEMBL29485605 0.91 BACE1 (0.71) BCL2L1MMP3BACE1ALOX5HSD17B1
SCHEMBL28293173 0.91 BACE1 (0.71) BCL2L1MMP3BACE1ALOX5HSD17B1
SCHEMBL344800 0.91 BACE1 (0.71) BCL2L1MMP3BACE1ALOX5HSD17B1
SCHEMBL9504663 0.89 ALOX5 (0.65) BCL2L1MMP3BACE1ALOX5HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103524467-B Containing ester group tetracarboxylic acid dianhydride, polyester-imide precursor, polyester-imide and manufacture method thereof HONSHU CHEMICAL IND (JP) 2015-10-28 CN disclosed
US-9096566-B2 Ester group-containing tetracarboxylic acid dianhydride, polyester polyimide precursor, polyesterimide, and methods for producing same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2015-08-04 US disclosed
US-9096566-B2 Ester group-containing tetracarboxylic acid dianhydride, polyester polyimide precursor, polyesterimide, and methods for producing same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2015-08-04 US disclosed
US-9096566-B2 Ester group-containing tetracarboxylic acid dianhydride, polyester polyimide precursor, polyesterimide, and methods for producing same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2015-08-04 US disclosed
CN-102234256-B Novel diepoxide HONSHU CHEMICAL IND 2014-12-10 CN disclosed
CN-103524467-A Ester group-containing tetracarboxylic dianhydride, polyimide precursor polyester, polyester imide and its manufacturing method HONSHU CHEMICAL IND 2014-01-22 CN disclosed
US-20120029164-A1 ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, POLYESTER POLYIMIDE PRECURSOR, POLYESTERIMIDE, AND METHODS FOR PRODUCING SAME HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-02-02 US disclosed
US-20120029164-A1 ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, POLYESTER POLYIMIDE PRECURSOR, POLYESTERIMIDE, AND METHODS FOR PRODUCING SAME HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-02-02 US disclosed
US-20120029164-A1 ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, POLYESTER POLYIMIDE PRECURSOR, POLYESTERIMIDE, AND METHODS FOR PRODUCING SAME HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-02-02 US disclosed
CN-102234256-A Novel diepoxide HONSHU CHEMICAL IND 2011-11-09 CN disclosed
EP-1375461-B1 DIPHENOL AND PROCESS FOR PRODUCING THE SAME HONSHU CHEMICAL IND (JP) 2009-08-05 EP disclosed
US-6872858-B2 Diphenol and process for producing the same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2005-03-29 US disclosed
US-20040049086-A1 Diphenol and process for producing the same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2004-03-11 US disclosed
EP-1375461-A1 DIPHENOL AND PROCESS FOR PRODUCING THE SAME Honshu Chemical Industry Co. Ltd. (JP) 2004-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029164-A1 ESTER GROUP-CONTAINING TETRACARBOXYLIC ACID DIANHYDRIDE, POLYESTER POLYIMIDE PRECURSOR, POLYESTERIMIDE, AND METHODS FOR PRODUCING SAME ALK, ALKBH3, IGLV6-57 BCL2L1 3830/4885MMP3 4755/4885BACE1 4178/4885
US-20040049086-A1 Diphenol and process for producing the same CYP1A1, AHR, CYP2E1 BCL2L1 3453/4885MMP3 4725/4885BACE1 1458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.