SCHEMBL28293245

SCHEMBL28293245

CNC(=O)C1(OC(=O)NC(C)(C)C)CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28295052 0.83 ALDH1A1 (0.31) ALDH1A1SMN1; SMN2
SCHEMBL28034764 0.81 ACHE (0.32) ALDH1A1
SCHEMBL28046351 0.79 ALDH1A1 (0.30) ALDH1A1
SCHEMBL28035335 0.77 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL28035333 0.77
SCHEMBL28035297 0.76
Hydrochloric Acid SCHEMBL27887431 0.75
SCHEMBL28034738 0.75
SCHEMBL27852084 0.74 EPHX1 (0.31)
SCHEMBL7819937 0.74 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790168-A SUBSTITUTED PYRROLIZINE COMPOUNDS AND USES THEREOF 吉利德科学公司 2019-05-21 CN disclosed