Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28061253 | 0.85 | NAAA (0.50) | DNM1NAAAEPHX1ACHETSHR | |
| SCHEMBL27941406 | 0.77 | DNM1 (0.41) | DNM1NAAADGKAEPHX1TSHR | |
| SCHEMBL27709794 | 0.75 | DNM1 (0.39) | DNM1NAAADGKAEPHX1TSHR | |
| SCHEMBL322523 | 0.74 | DNM1 (0.38) | DNM1TSHRALDH1A1 | |
| SCHEMBL10899443 | 0.74 | DNM1 (0.38) | DNM1TSHRALDH1A1 | |
| SCHEMBL10900689 | 0.74 | DNM1 (0.38) | DNM1TSHRALDH1A1 | |
| SCHEMBL28329411 | 0.73 | NAAA (0.52) | NAAAEPHX1ACHETSHRHTR2C | |
| SCHEMBL22558154 | 0.73 | NAAA (0.52) | NAAADGKAEPHX1ACHETSHR | |
| SCHEMBL22558002 | 0.73 | NAAA (0.52) | NAAADGKAEPHX1ACHETSHR | |
| SCHEMBL1865408 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028491-A | Fibroblast growth factor receptor inhibitor | 蓝图药品公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-105658642-B | Fibroblast growth factor receptor inhibitors | 蓝图药品公司 | 2019-05-03 | — | — | CN | disclosed |