SCHEMBL28293336

SCHEMBL28293336

Cc1cccc(S(=O)(=O)N(C(N)=O)c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
LMNA P02545 3/20 0.49
HCRTR2 O43614 1/20 0.45
GLA P06280 1/20 0.44
ALDH1A1 P00352 2/20 0.43
TP53 P04637 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
HSD17B10 Q99714 1/20 0.43
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KAT6A Q92794 1/20 0.42
USP2 O75604 1/20 0.41
MCL1 Q07820 1/20 0.40
TAS2R14 Q9NYV8 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6329247 0.87 PARP1 (0.47) KMT2ALMNAHCRTR2ALDH1A1TP53
SCHEMBL6323766 0.86 PARP1 (0.54) LMNAHCRTR2ALDH1A1TP53HPGD
SCHEMBL174224 0.84 KMT2A (0.62) KMT2AALDH1A1HPGD
SCHEMBL28244533 0.83 KMT2A (0.63) KMT2ALMNAALDH1A1TP53KEAP1
SCHEMBL1878018 0.83 CA12 (0.58) KMT2ALMNAALDH1A1TP53KEAP1
SCHEMBL28082161 0.82 TP53 (0.53) KMT2ALMNAHCRTR2ALDH1A1TP53
SCHEMBL6324948 0.82 LMNA (0.63) KMT2ALMNAHCRTR2ALDH1A1TP53
SCHEMBL7602168 0.82 CA12 (0.46) LMNAALDH1A1TP53HPGDPOLB
SCHEMBL28230825 0.80 CA12 (0.48) KMT2ALMNAALDH1A1TP53KEAP1
SCHEMBL6241748 0.79 LMNA (0.55) KMT2ALMNAALDH1A1TP53KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790108-A Thermal recording medium 奥古斯特科勒纸厂欧洲公司 2019-05-21 CN disclosed