SCHEMBL7602168

SCHEMBL7602168

COC(=O)c1cccc(N(C(N)=O)S(=O)(=O)c2cccc(C)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
TP53 P04637 1/20 0.45
LMNA P02545 3/20 0.44
TCF4 P15884 1/20 0.44
CTNNB1 P35222 1/20 0.44
CYP2C9 P11712 1/20 0.43
POLB P06746 1/20 0.41
GPR17 Q13304 1/20 0.41
ALDH1A1 P00352 3/20 0.41
GAA P10253 2/20 0.41
LOX P28300 1/20 0.41
RAB9A P51151 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.40
RORC P51449 1/20 0.40
KDM4E B2RXH2 1/20 0.40
PKM P14618 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6323766 0.88 PARP1 (0.54) TP53LMNAALDH1A1GAARAB9A
SCHEMBL7596654 0.82 CNR2 (0.43) LMNAALDH1A1RAB9A
SCHEMBL28293336 0.82 KMT2A (0.50) TP53LMNAPOLBALDH1A1HPGD
SCHEMBL6329247 0.79 PARP1 (0.47) TP53LMNAPOLBALDH1A1RAB9A
SCHEMBL6324948 0.77 LMNA (0.63) CA12CA9TP53LMNAPOLB
SCHEMBL6326721 0.76 TP53 (0.53) CA12CA9TP53LMNARORC
SCHEMBL7597834 0.74 LMNA (0.51) LMNAALDH1A1KDM4E
SCHEMBL6324423 0.74 KMT2A (0.46) TP53LMNAPOLBALDH1A1GAA
SCHEMBL6241748 0.74 LMNA (0.55) CA12CA9TP53LMNACYP2C9
SCHEMBL7601325 0.73 MAPT (0.53) TP53LMNAPOLBALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed