Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.92 |
| ▸ | TSHR | P16473 | 2/20 | 0.92 |
| ▸ | GLA | P06280 | 1/20 | 0.92 |
| ▸ | HPGD | P15428 | 1/20 | 0.92 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.92 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.92 |
| ▸ | BLM | P54132 | 1/20 | 0.92 |
| ▸ | CA1 | P00915 | 10/20 | 0.55 |
| ▸ | CA2 | P00918 | 10/20 | 0.55 |
| ▸ | CA9 | Q16790 | 8/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA7 | P43166 | 3/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.55 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.41 |
| ▸ | FGF1 | P05230 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28277065 | 0.98 | RECQL (0.96) | RECQLTSHRGLAHPGDMAPK1 | |
| Water SCHEMBL27678765 | 0.98 | RECQL (0.96) | RECQLTSHRGLAHPGDMAPK1 | |
| Water SCHEMBL1023737 | 0.98 | RECQL (0.96) | RECQLTSHRGLAHPGDMAPK1 | |
| Water SCHEMBL771625 | 0.98 | RECQL (0.96) | RECQLTSHRGLAHPGDMAPK1 | |
| Water SCHEMBL669056 | 0.98 | RECQL (0.96) | RECQLTSHRGLAHPGDMAPK1 | |
| Water SCHEMBL7534502 | 0.98 | RECQL (0.96) | RECQLTSHRGLAHPGDMAPK1 | |
| Octadecyl Sulfate SCHEMBL739215 | 0.98 | RECQL (0.96) | RECQLTSHRGLAHPGDMAPK1 | |
| Water SCHEMBL28352580 | 0.98 | RECQL (0.96) | RECQLTSHRGLAHPGDMAPK1 | |
| Ammonia Solution, Strong SCHEMBL8824186 | 0.98 | RECQL (0.96) | RECQLTSHRGLAHPGDMAPK1 | |
| Water SCHEMBL10868534 | 0.98 | RECQL (0.96) | RECQLTSHRGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110054950-A | A kind of acrylic wall emulsion paint and its preparation process | 上海雷鸟涂料有限公司 | 2019-07-26 | — | — | CN | disclosed |
| CN-109734826-A | A kind of preparation method of biomass anacardol internal plasticization hydrogenated nitrile-butadiene rubber | 沈阳化工大学 | 2019-05-10 | — | — | CN | disclosed |