⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154719 | 0.69 | — | — | |
| SCHEMBL5009936 | 0.69 | — | — | |
| SCHEMBL7253514 | 0.67 | — | — | |
| SCHEMBL28276659 | 0.65 | — | — | |
| SCHEMBL27452119 | 0.65 | — | — | |
| SCHEMBL5173065 | 0.65 | — | — | |
| SCHEMBL5174500 | 0.65 | — | — | |
| SCHEMBL162194 | 0.60 | — | — | |
| SCHEMBL7248101 | 0.60 | GABRA1 (0.44) | — | |
| SCHEMBL163392 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109983006-A | Crystalline forms of lysyl oxidase-like 2 inhibitors and methods of making the same | 法玛克亚公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-109922803-A | Use of lysyl oxidase-like 2 inhibitors | 法玛克亚公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-106458985-B | 6-heteroaryloxy-and 6-aryloxy-quinoline-2-carboxamides and their use | 艾伯维公司 | 2019-05-03 | — | — | CN | disclosed |