Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF2 | P09038 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14994782 | 0.85 | SMN1; SMN2 (0.49) | FGF2ALDH1A1SMN1; SMN2HTTHPGD | |
| SCHEMBL3684078 | 0.82 | ALDH1A1 (0.49) | FGF2ALDH1A1SMN1; SMN2HTTHPGD | |
| SCHEMBL19029829 | 0.80 | MEN1 (0.44) | FGF2ALDH1A1SMN1; SMN2HTTHPGD | |
| SCHEMBL31112932 | 0.80 | ALDH1A1 (0.45) | FGF2ALDH1A1SMN1; SMN2HTTHPGD | |
| SCHEMBL19029776 | 0.78 | HCAR2 (0.49) | FGF2ALDH1A1SMN1; SMN2HTTHPGD | |
| SCHEMBL19029793 | 0.78 | HCAR2 (0.49) | FGF2ALDH1A1SMN1; SMN2HTTHPGD | |
| SCHEMBL26620226 | 0.78 | HCAR2 (0.49) | FGF2ALDH1A1SMN1; SMN2HTTHPGD | |
| SCHEMBL1403557 | 0.77 | ALDH1A1 (0.47) | FGF2ALDH1A1SMN1; SMN2HTTHPGD | |
| SCHEMBL14865371 | 0.77 | POLB (0.53) | FGF2ALDH1A1SMN1; SMN2HTTHPGD | |
| SCHEMBL24777173 | 0.76 | ALDH1A1 (0.45) | FGF2ALDH1A1SMN1; SMN2HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831529-A | Preparation method of monomethoxy polyethylene glycol carboxylic acid and functional derivative thereof | 江苏众红生物工程创药研究院有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-113831529-A | Preparation method of monomethoxy polyethylene glycol carboxylic acid and functional derivative thereof | 江苏众红生物工程创药研究院有限公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-113831529-A | Preparation method of monomethoxy polyethylene glycol carboxylic acid and functional derivative thereof | 江苏众红生物工程创药研究院有限公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-109608633-A | A kind of novel specific multi-arm polyethylene glycol derivative and preparation method thereof | 北京诺康达医药科技股份有限公司 | 2019-04-12 | — | — | CN | disclosed |