Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FGF2 | P09038 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ENO1 | P06733 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14094402 | 0.85 | ALDH1A1 (0.43) | POLBGAANPSR1ALDH1A1HPGD | |
| SCHEMBL5511917 | 0.83 | ALDH1A1 (0.40) | POLBGAANPSR1ALDH1A1HPGD | |
| SCHEMBL3684078 | 0.79 | ALDH1A1 (0.49) | GAAALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL16769831 | 0.79 | ALDH1A1 (0.39) | POLBGAANPSR1ALDH1A1HPGD | |
| SCHEMBL9914134 | 0.79 | NPSR1 (0.57) | POLBGAANPSR1ALDH1A1HPGD | |
| SCHEMBL28293612 | 0.77 | FGF2 (0.45) | POLBALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL18457392 | 0.77 | POLB (0.48) | POLBGAANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29362852 | 0.75 | POLB (0.38) | POLBGAANPSR1ALDH1A1HPGD | |
| SCHEMBL3106135 | 0.75 | POLB (0.42) | POLBGAANPSR1SMN1; SMN2ENO1 | |
| SCHEMBL31112932 | 0.74 | ALDH1A1 (0.45) | POLBALDH1A1HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806342-B1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2013-04-17 | — | — | EP | disclosed |