Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.47 |
| ▸ | ERN1 | O75460 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189636 | 0.87 | ORAI1 (0.51) | ORAI1ERN1POLBCYP1A2TDP1 | |
| SCHEMBL3222717 | 0.84 | ORAI1 (0.49) | ORAI1ERN1POLBCYP1A2TDP1 | |
| SCHEMBL17513175 | 0.81 | ORAI1 (0.56) | ORAI1ERN1POLBCYP1A2TDP1 | |
| SCHEMBL16005185 | 0.79 | ORAI1 (0.54) | ORAI1ERN1POLBCYP1A2TDP1 | |
| SCHEMBL8198170 | 0.79 | ERN1 (0.65) | ORAI1ERN1POLBCYP1A2ALDH1A1 | |
| SCHEMBL11781754 | 0.78 | ALDH1A1 (0.57) | ORAI1ERN1CYP1A2TDP1ALDH1A1 | |
| SCHEMBL16005448 | 0.77 | ORAI1 (0.52) | ORAI1ERN1POLBCYP1A2TDP1 | |
| SCHEMBL1186559 | 0.75 | HPGD (0.50) | ERN1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL5882741 | 0.75 | ALDH1A1 (0.46) | ORAI1ERN1CYP1A2TDP1ALDH1A1 | |
| SCHEMBL31551028 | 0.74 | ERN1 (0.53) | ORAI1ERN1CYP1A2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104045552-B | Medicinal compound as neuroprotective agent | 江苏先声药业有限公司 | 2019-06-11 | — | — | CN | disclosed |