Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PTPRA | P18433 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL28196672 | 0.89 | L3MBTL1 (0.49) | L3MBTL1TDP1LMNAPOLBKMT2A | |
| SCHEMBL64435 | 0.88 | L3MBTL1 (0.68) | L3MBTL1TDP1LMNAPOLBCYP1A2 | |
| SCHEMBL29373231 | 0.88 | L3MBTL1 (0.68) | L3MBTL1TDP1LMNAPOLBCYP1A2 | |
| Hydrochloric Acid SCHEMBL7252291 | 0.86 | L3MBTL1 (0.71) | L3MBTL1LMNAPOLBCYP1A2CYP2D6 | |
| SCHEMBL31276017 | 0.86 | L3MBTL1 (0.66) | L3MBTL1LMNAPOLBCYP1A2CYP2D6 | |
| SCHEMBL30021715 | 0.86 | L3MBTL1 (0.66) | L3MBTL1TDP1LMNAPOLBCYP1A2 | |
| SCHEMBL29985764 | 0.86 | L3MBTL1 (0.66) | L3MBTL1TDP1LMNAPOLBCYP1A2 | |
| Hydrochloric Acid SCHEMBL31087535 | 0.86 | L3MBTL1 (0.71) | L3MBTL1LMNAPOLBCYP1A2CYP2D6 | |
| Bromide SCHEMBL10759788 | 0.86 | L3MBTL1 (0.66) | L3MBTL1TDP1LMNAPOLBCYP1A2 | |
| SCHEMBL31236458 | 0.86 | L3MBTL1 (0.66) | L3MBTL1TDP1LMNAPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651238-A | A kind of new method preparing picosulfate sodium | 杭州新博思生物医药有限公司 | 2019-04-19 | — | — | CN | disclosed |