Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28293743

CC(C)(C)c1ccc2[nH]c3ccccc3c2c1.N

nearest known ligand 0.96

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 13/20 0.96
AHR P35869 1/20 0.55
ALDH1A1 P00352 2/20 0.52
HSD17B10 Q99714 2/20 0.52
GPR3 P46089 1/20 0.52
KDM4E B2RXH2 2/20 0.51
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
MAPT P10636 1/20 0.51
HPGD P15428 1/20 0.51
MTNR1A P48039 1/20 0.49
MTNR1B P49286 1/20 0.49
GABRA1 P14867 1/20 0.47
GABRG2 P18507 1/20 0.47
GABRB3 P28472 1/20 0.47
GABRA5 P31644 1/20 0.47
GABRA3 P34903 1/20 0.47
GABRA2 P47869 1/20 0.47
GABRA4 P48169 1/20 0.47
GABRA6 Q16445 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363588 0.98 KIF11 (1.00) KIF11AHRALDH1A1HSD17B10GPR3
Carbazole SCHEMBL28794196 0.98 KIF11 (1.00) KIF11AHRALDH1A1HSD17B10GPR3
SCHEMBL29588087 0.98 KIF11 (1.00) KIF11AHRALDH1A1HSD17B10GPR3
SCHEMBL10090582 0.98 KIF11 (1.00) KIF11AHRALDH1A1HSD17B10GPR3
SCHEMBL20232390 0.92 KIF11 (0.89) KIF11AHRALDH1A1HSD17B10GPR3
Ammonia Solution, Strong SCHEMBL25176966 0.90 KIF11 (0.78) KIF11ALDH1A1HSD17B10KDM4EKMT2A
SCHEMBL29535 0.88 KIF11 (0.81) KIF11ALDH1A1HSD17B10KDM4EKMT2A
SCHEMBL29361452 0.88 KIF11 (0.81) KIF11ALDH1A1HSD17B10KDM4EKMT2A
SCHEMBL29362207 0.87 KIF11 (1.00) KIF11AHRALDH1A1HSD17B10GPR3
SCHEMBL10312973 0.87 KIF11 (1.00) KIF11AHRALDH1A1HSD17B10GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106467511-B It is a kind of using acridone as the compound of core and its application on organic electroluminescence device 江苏三月光电科技有限公司 2019-04-19 CN disclosed