SCHEMBL10312973

SCHEMBL10312973

CC(C)(C)c1ccc2c(c1)[nH]c1ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 16/20 1.00
AHR P35869 1/20 0.57
ALDH1A1 P00352 1/20 0.54
GPR3 P46089 1/20 0.54
HSD17B10 Q99714 1/20 0.54
PLK4 O00444 1/20 0.48
CHEK1 O14757 1/20 0.48
AURKA O14965 1/20 0.48
CHUK O15111 1/20 0.48
PDPK1 O15530 1/20 0.48
JAK2 O60674 1/20 0.48
ROCK2 O75116 1/20 0.48
MAP4K4 O95819 1/20 0.48
PAK4 O96013 1/20 0.48
CHEK2 O96017 1/20 0.48
ABL1 P00519 1/20 0.48
NTRK1 P04629 1/20 0.48
PRKCG P05129 1/20 0.48
INSR P06213 1/20 0.48
LCK P06239 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362207 1.00 KIF11 (1.00) KIF11AHRALDH1A1GPR3HSD17B10
SCHEMBL2606005 0.90 KIF11 (0.81) KIF11ALDH1A1HSD17B10
SCHEMBL29539315 0.90 KIF11 (0.81) KIF11ALDH1A1HSD17B10
SCHEMBL29588087 0.89 KIF11 (1.00) KIF11AHRALDH1A1GPR3HSD17B10
Carbazole SCHEMBL28794196 0.89 KIF11 (1.00) KIF11AHRALDH1A1GPR3HSD17B10
SCHEMBL29363588 0.89 KIF11 (1.00) KIF11AHRALDH1A1GPR3HSD17B10
SCHEMBL10090582 0.89 KIF11 (1.00) KIF11AHRALDH1A1GPR3HSD17B10
Bromide SCHEMBL30567841 0.88 KIF11 (0.78) KIF11ALDH1A1HSD17B10
Ammonia Solution, Strong SCHEMBL28293743 0.87 KIF11 (0.96) KIF11AHRALDH1A1GPR3HSD17B10
SCHEMBL23327761 0.86 KIF11 (0.76) KIF11AHRCHUK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107935913-A Carbazole compound and its synthetic method and application 华东师范大学 2018-04-20 CN claimed
EP-3728239-B1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2026-05-20 EP disclosed
US-12635331-B2 Organic electroluminescent device emitting light SAMSUNG DISPLAY CO., LTD. (KR) 2026-05-19 US disclosed
EP-3670507-B1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2026-05-06 EP disclosed
EP-4709112-A2 ORGANIC ELECTROLUMINESCENT DEVICE Samsung Display Co., Ltd. (KR) 2026-03-11 EP disclosed
EP-4709113-A2 ORGANIC ELECTROLUMINESCENT DEVICE Samsung Display Co., Ltd. (KR) 2026-03-11 EP disclosed
EP-4214766-B1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO LTD (KR) 2026-03-04 EP disclosed
EP-4214779-B1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO LTD (KR) 2026-02-18 EP disclosed
EP-4692276-A2 ORGANIC MOLECULES WITH A TRIFLUOROMETHYL-BIPHENYL CORE FOR USE IN OPTOELECTRONIC DEVICES Samsung Display Co., Ltd. (KR) 2026-02-11 EP disclosed
EP-3724181-B1 ORGANIC MOLECULES WITH A TRIFLUOROMETHYL-BIPHENYL CORE FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2026-01-28 EP disclosed
US-7939666-B2 Enzyme inhibitors CHROMA THERAPEUTICS LTD. (GB) 2011-05-10 US disclosed
US-7932246-B2 Histone deacetylase inhibitors CHROMA THERAPEUTICS LTD. (GB) 2011-04-26 US disclosed
US-20100317678-A1 HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE CHROMA THERAPEUTICS LTD. (GB) 2010-12-16 US disclosed
US-20100244676-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
US-20100244676-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
US-20100152155-A1 Histone Deacetylase Inhibitors CHROMA THERAPEUTICS LTD. (GB) 2010-06-17 US disclosed
US-20090298924-A1 HYDROXAMIC ACID DERIVATIVES AS INHIBITORS OF HDAC ENZYMATIC ACTIVITY CHROMA THERAPEUTICS LTD (GB) 2009-12-03 US disclosed
US-20090298924-A1 HYDROXAMIC ACID DERIVATIVES AS INHIBITORS OF HDAC ENZYMATIC ACTIVITY CHROMA THERAPEUTICS LTD (GB) 2009-12-03 US disclosed
US-20090291978-A1 Enzyme Inhibitors CHROMA THERAPEUTICS LTD. (GB) 2009-11-26 US disclosed
US-20090291978-A1 Enzyme Inhibitors CHROMA THERAPEUTICS LTD. (GB) 2009-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317678-A1 HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE H1-2, HDAC1, H1-0 KIF11 3276/4885AHR 777/4885ALDH1A1 724/4885
US-20090298924-A1 HYDROXAMIC ACID DERIVATIVES AS INHIBITORS OF HDAC ENZYMATIC ACTIVITY HDAC1, HDAC3, HAT1 KIF11 4537/4885AHR 138/4885ALDH1A1 348/4885
US-12635331-B2 Organic electroluminescent device emitting light HBS1L, ETFB, EPHB3 KIF11 2602/4885AHR 1989/4885ALDH1A1 1485/4885
US-20090291978-A1 Enzyme Inhibitors HAT1, NR2E1, NR2C2 KIF11 4724/4885AHR 813/4885ALDH1A1 1343/4885
US-20100152155-A1 Histone Deacetylase Inhibitors HDAC1, HDAC2, HDAC11 KIF11 1861/4885AHR 1544/4885ALDH1A1 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.