Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1545922 | 0.86 | MMP8 (0.53) | MMP8GAAMEN1NPC1KMT2A | |
| SCHEMBL1244623 | 0.85 | TSHR (0.55) | MMP8GAAMEN1NPC1KMT2A | |
| SCHEMBL28763045 | 0.85 | MMP8 (0.51) | MMP8GAAMEN1NPC1KMT2A | |
| SCHEMBL10387080 | 0.84 | SMN1; SMN2 (0.48) | MMP8GAAMEN1NPC1KMT2A | |
| SCHEMBL28134460 | 0.83 | SMN1; SMN2 (0.53) | MMP8GAAMEN1NPC1KMT2A | |
| SCHEMBL23027214 | 0.82 | GAA (0.62) | MMP8GAAMEN1KMT2APIN1 | |
| SCHEMBL805646 | 0.82 | GAA (0.62) | MMP8GAAMEN1KMT2APIN1 | |
| SCHEMBL5972492 | 0.82 | MMP8 (0.56) | MMP8GAAMEN1NPC1KMT2A | |
| SCHEMBL260296 | 0.82 | GAA (0.62) | MMP8GAAMEN1KMT2APIN1 | |
| SCHEMBL6250715 | 0.82 | KMT2A (0.69) | MMP8GAAMEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678902-A | One kind has the organic catalyst, ligand and synthesis and application of rigid spiral shell [indane -1,2 '-pyrrolidines] skeleton | 北京师范大学 | 2019-04-26 | — | — | CN | disclosed |