Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1545922 | 0.88 | MMP8 (0.53) | MMP8MEN1NPC1KMT2AGAA | |
| SCHEMBL1244623 | 0.86 | TSHR (0.55) | MMP8MEN1NPC1KMT2AGAA | |
| SCHEMBL28293753 | 0.85 | MMP8 (0.50) | MMP8MEN1NPC1KMT2AGAA | |
| SCHEMBL28134460 | 0.85 | SMN1; SMN2 (0.53) | MMP8MEN1NPC1KMT2AGAA | |
| SCHEMBL13175572 | 0.84 | KMT2A (0.56) | MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL27891936 | 0.84 | KMT2A (0.56) | MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL4807273 | 0.84 | ALDH1A1 (0.42) | MMP8MEN1NPC1KMT2AGAA | |
| SCHEMBL23027214 | 0.84 | GAA (0.62) | MMP8MEN1KMT2AGAAPIN1 | |
| SCHEMBL805646 | 0.84 | GAA (0.62) | MMP8MEN1KMT2AGAAPIN1 | |
| SCHEMBL5972492 | 0.84 | MMP8 (0.56) | MMP8MEN1NPC1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100491354-C | Quinoline kind iriyellowsin electronic isostere and its preparation process and use | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2009-05-27 | — | — | CN | disclosed |
| CN-100999492-A | Quinoline kind iriyellowsin electronic isostericmer its preparation process and use | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2007-07-18 | — | — | CN | disclosed |