SCHEMBL28293808

SCHEMBL28293808

CCCCC[Si](OC)(OC)OCc1ccc(F)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 1/20 0.39
HSP90AA1 P07900 1/20 0.39
MMP2 P08253 1/20 0.39
MC4R P32245 1/20 0.39
RAD52 P43351 1/20 0.39
IDO1 P14902 2/20 0.38
AGXT P21549 2/20 0.38
HPGD P15428 1/20 0.38
LMNA P02545 1/20 0.36
MAOB P27338 1/20 0.36
FAAH O00519 1/20 0.35
GAA P10253 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
KCNH3 Q9ULD8 1/20 0.33
HTR7 P34969 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28136105 0.79 CETP (0.40) IDO1LMNAALDH1A1
SCHEMBL15733865 0.78 ALDH1A1 (0.36) HPGDGAAALDH1A1MAPTHTT
SCHEMBL15737837 0.77 ALDH1A1 (0.35) HPGDLMNAGAAALDH1A1MAPT
SCHEMBL15736942 0.77 ALDH1A1 (0.35) HPGDLMNAGAAALDH1A1MAPT
SCHEMBL15738631 0.76 TAAR1 (0.37) HPGDGAAALDH1A1MAPTHTT
SCHEMBL3631052 0.76 IDO1 (0.41) PSMD14HSP90AA1MMP2MC4RRAD52
SCHEMBL15737395 0.75 ALDH1A1 (0.36) HPGDGAAALDH1A1MAPTHTT
SCHEMBL15735870 0.75 TAAR1 (0.41) GAAALDH1A1MAPTKMT2A
SCHEMBL15737957 0.74 ALDH1A1 (0.35) HPGDLMNAGAAALDH1A1MAPT
SCHEMBL15738900 0.74 ALDH1A1 (0.35) HPGDLMNAGAAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109872830-A Production method for the surface modifier of metal electrode, surface-modified metal electrode and surface-modified metal electrode 信越化学工业株式会社 2019-06-11 CN disclosed