SCHEMBL28293810

SCHEMBL28293810

C=C(CCl)C(=O)OCc1cccc(OC)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
MMP1 P03956 2/20 0.51
MMP2 P08253 2/20 0.51
MMP9 P14780 2/20 0.51
MMP12 P39900 2/20 0.51
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
IDO1 P14902 2/20 0.49
AGXT P21549 2/20 0.49
MTNR1A P48039 2/20 0.46
MTNR1B P49286 2/20 0.46
MRGPRX4 Q96LA9 1/20 0.46
CYP1A2 P05177 1/20 0.45
THRB P10828 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27699824 0.84 MMP1 (0.54) ALDH1A1HTTSMN1; SMN2MMP1MMP2
SCHEMBL30486011 0.84 MMP1 (0.54) ALDH1A1HTTSMN1; SMN2MMP1MMP2
SCHEMBL5072089 0.84 MMP1 (0.54) ALDH1A1HTTSMN1; SMN2MMP1MMP2
SCHEMBL27263548 0.83 GAA (0.51) ALDH1A1SMN1; SMN2MMP1MMP2MMP9
SCHEMBL27281567 0.82 NPC1 (0.53) ALDH1A1MMP1MMP2MMP9MMP12
SCHEMBL28295722 0.81 ALDH1A1 (0.50) ALDH1A1HTTSMN1; SMN2RAB9AMTNR1A
SCHEMBL5526159 0.79 MMP1 (0.58) ALDH1A1HTTSMN1; SMN2MMP1MMP2
SCHEMBL28556983 0.79 MMP1 (0.61) ALDH1A1HTTSMN1; SMN2MMP1MMP2
SCHEMBL31326237 0.79 MMP1 (0.61) ALDH1A1HTTSMN1; SMN2MMP1MMP2
SCHEMBL10242013 0.77 IDO1 (0.59) MMP1MMP2MMP9MMP12NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109678804-A A method of preparing fluacrypyrim 柳州市惠农化工有限公司 2019-04-26 CN claimed
CN-102030710-A Method for synthesizing 14 C-labeled compound of pyraoxystrobin serving as bactericide UNIV ZHEJIANG 2011-04-27 CN claimed
CN-109678804-A A method of preparing fluacrypyrim 柳州市惠农化工有限公司 2019-04-26 CN disclosed
CN-109678804-A A method of preparing fluacrypyrim 柳州市惠农化工有限公司 2019-04-26 CN disclosed
CN-102030710-A Method for synthesizing 14 C-labeled compound of pyraoxystrobin serving as bactericide UNIV ZHEJIANG 2011-04-27 CN disclosed