Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 10/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7190069 | 0.80 | PADI4 (0.52) | PADI4ERN1TRIM24TRIM33MCL1 | |
| SCHEMBL9353882 | 0.79 | PADI4 (0.50) | PADI4ERN1TRIM24TRIM33MCL1 | |
| SCHEMBL8974313 | 0.76 | HTT (0.57) | PADI4ERN1TRIM24TRIM33MCL1 | |
| SCHEMBL1001765 | 0.71 | ERN1 (0.55) | ERN1MCL1 | |
| SCHEMBL29708011 | 0.71 | ERN1 (0.55) | ERN1MCL1 | |
| SCHEMBL7756770 | 0.71 | ERN1 (0.43) | PADI4ERN1TRIM24TRIM33MCL1 | |
| SCHEMBL5663780 | 0.71 | ERN1 (0.43) | PADI4ERN1TRIM24TRIM33MCL1 | |
| SCHEMBL8416094 | 0.71 | LMNA (0.50) | PADI4ERN1TRIM24TRIM33MCL1 | |
| SCHEMBL28467801 | 0.70 | HSD17B10 (0.59) | MCL1THRBMEN1LMNAKMT2A | |
| SCHEMBL5663542 | 0.70 | PTPN1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734642-B | Synthesis and application of naphthalenone-sulfoxide ylide hybrid | 河南师范大学 | 2020-10-09 | — | — | CN | claimed |
| CN-109734642-A | Naphthalenone-sulfoxide ylide hybrid synthesis and application | 河南师范大学 | 2019-05-10 | — | — | CN | claimed |
| CN-109734642-B | Synthesis and application of naphthalenone-sulfoxide ylide hybrid | 河南师范大学 | 2020-10-09 | — | — | CN | disclosed |
| CN-109734642-B | Synthesis and application of naphthalenone-sulfoxide ylide hybrid | 河南师范大学 | 2020-10-09 | — | — | CN | disclosed |
| CN-109734642-A | Naphthalenone-sulfoxide ylide hybrid synthesis and application | 河南师范大学 | 2019-05-10 | — | — | CN | disclosed |
| CN-109734642-A | Naphthalenone-sulfoxide ylide hybrid synthesis and application | 河南师范大学 | 2019-05-10 | — | — | CN | disclosed |