SCHEMBL7190069

SCHEMBL7190069

O=Cc1cc(C=O)c2ccccc2c1O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PADI4 Q9UM07 1/20 0.52
ERN1 O75460 13/20 0.50
TRIM24 O15164 1/20 0.46
TRIM33 Q9UPN9 1/20 0.46
MCL1 Q07820 1/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.44
BLM P54132 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9353882 0.85 PADI4 (0.50) PADI4ERN1TRIM24TRIM33MCL1
SCHEMBL8416094 0.85 LMNA (0.50) PADI4ERN1TRIM24TRIM33MCL1
SCHEMBL22721454 0.83 ERN1 (0.52) PADI4ERN1TRIM24TRIM33
SCHEMBL8974313 0.82 HTT (0.57) PADI4ERN1TRIM24TRIM33MCL1
SCHEMBL7918991 0.82 MEN1 (0.53) PADI4ERN1TRIM24TRIM33MEN1
SCHEMBL19792630 0.82 ERN1 (0.50) PADI4ERN1TRIM24TRIM33MEN1
SCHEMBL9721295 0.80 HPGD (0.46) PADI4ERN1TRIM24TRIM33MEN1
SCHEMBL31339466 0.80 HPGD (0.46) PADI4ERN1TRIM24TRIM33MEN1
SCHEMBL28293873 0.80 PADI4 (0.46) PADI4ERN1TRIM24TRIM33MCL1
SCHEMBL5663542 0.80 PTPN1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 PADI4 4800/4885ERN1 4751/4885TRIM24 4167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.