Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28238926 | 0.93 | ALDH1A1 (0.48) | ALDH1A1PEPDTSHRTHRBTDP1 | |
| Methacrylic Acid SCHEMBL6017696 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBTDP1ELANE | |
| Methacrylic Acid SCHEMBL13726862 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBTDP1ELANE | |
| Methacrylic Acid SCHEMBL28105268 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBTDP1ELANE | |
| Methacrylic Acid SCHEMBL28034418 | 0.88 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRBTDP1ELANE | |
| Phosphoric Acid SCHEMBL10716549 | 0.84 | TSHR (0.42) | ALDH1A1TSHRTHRB | |
| Phosphoric Acid SCHEMBL10797377 | 0.84 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRB | |
| Acetic Acid SCHEMBL27477221 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRBTDP1ELANE | |
| Methacrylic Acid SCHEMBL7649955 | 0.83 | PEPD (0.43) | ALDH1A1PEPDTSHRTDP1 | |
| Methacrylic Acid SCHEMBL5805125 | 0.83 | PEPD (0.43) | ALDH1A1PEPDTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641997-A | Curable resin composition, fuel cell using the same, and sealing method | 三键有限公司 | 2019-04-16 | — | — | CN | disclosed |