Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17461311 | 0.80 | NOTUM (0.53) | NOTUMHTR2CKDM4EMEN1MAPT | |
| SCHEMBL30519847 | 0.78 | NOTUM (0.43) | NOTUMHTR2CGABRA1GABRB2KDM4E | |
| SCHEMBL1451551 | 0.78 | NOTUM (0.43) | NOTUMHTR2CGABRA1GABRB2KDM4E | |
| SCHEMBL6334445 | 0.77 | NOTUM (0.42) | NOTUMHTR2CGABRA1GABRB2KDM4E | |
| SCHEMBL28035819 | 0.77 | NOTUM (0.42) | NOTUMHTR2CGABRA1GABRB2KDM4E | |
| SCHEMBL2625755 | 0.74 | RARA (0.48) | NOTUMHTR2CGABRA1GABRB2KDM4E | |
| SCHEMBL13209366 | 0.74 | NOTUM (0.40) | NOTUMHTR2CGABRA1GABRB2KDM4E | |
| SCHEMBL13227696 | 0.74 | HTR2C (0.41) | NOTUMHTR2CGABRA1GABRB2KDM4E | |
| SCHEMBL21051639 | 0.73 | NOTUM (0.42) | NOTUMHTR2CGABRA1GABRB2KDM4E | |
| SCHEMBL1572418 | 0.73 | ADRA2C (0.47) | NOTUMHTR2CGABRA1GABRB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843291-A | synthetic retinoids (cell modulation) | 杜伦大学 | 2019-06-04 | — | — | CN | disclosed |