Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | TLR4 | O00206 | 2/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293910 | 0.90 | TSHR (0.39) | TSHRPLA2G4BLMNAALDH1A1MEN1 | |
| SCHEMBL28295755 | 0.85 | TSHR (0.40) | TSHRPLA2G4BLMNAALDH1A1MEN1 | |
| SCHEMBL28293899 | 0.80 | THRA (0.36) | TSHRPLA2G4BLMNAALDH1A1MEN1 | |
| SCHEMBL28295750 | 0.80 | LTA4H (0.39) | TSHRPLA2G4BLMNAALDH1A1MEN1 | |
| SCHEMBL28293909 | 0.78 | TSHR (0.41) | TSHRPLA2G4BLMNAALDH1A1MEN1 | |
| SCHEMBL1419945 | 0.75 | BID (0.49) | TSHRALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL15176184 | 0.73 | TSHR (0.40) | TSHRLMNAALDH1A1 | |
| SCHEMBL2712841 | 0.73 | TSHR (0.45) | TSHRLMNAALDH1A1MEN1NR1I2 | |
| SCHEMBL342807 | 0.72 | PTPN11 (0.52) | TSHRPLA2G4BLMNAALDH1A1MEN1 | |
| SCHEMBL11330301 | 0.72 | PTPN11 (0.52) | TSHRPLA2G4BLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790190-A | Curing agent for silicone rubber material | 硝基化学阿绍有限公司 | 2019-05-21 | — | — | CN | claimed |
| CN-109790190-A | Curing agent for silicone rubber material | 硝基化学阿绍有限公司 | 2019-05-21 | — | — | CN | disclosed |