Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | S100A4 | P26447 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1207550 | 0.85 | DPP4 (0.57) | DPP4S100A4CDC25BCYP2A6PTPRC | |
| SCHEMBL4160810 | 0.84 | CYP2A6 (0.52) | S100A4CDC25BCYP2A6PTPRCCTSL | |
| SCHEMBL20821396 | 0.84 | DPP4 (0.65) | DPP4S100A4CDC25BCYP2A6PTPRC | |
| SCHEMBL17033052 | 0.82 | DPP4 (0.41) | DPP4S100A4CDC25BCYP2A6TDP2 | |
| SCHEMBL28309616 | 0.82 | PTPRC (0.50) | S100A4CDC25BCYP2A6PTPRCCTSL | |
| SCHEMBL28329987 | 0.78 | KCNA5 (0.47) | DPP4S100A4CDC25BCYP2A6TDP2 | |
| SCHEMBL28622449 | 0.78 | DPP4 (0.49) | DPP4S100A4CDC25BPTPRCCTSL | |
| SCHEMBL28484220 | 0.78 | ESR2 (0.47) | MEN1KMT2APDE2A | |
| SCHEMBL22947724 | 0.77 | CYP2A6 (0.54) | DPP4S100A4CDC25BCYP2A6PTPRC | |
| SCHEMBL30021754 | 0.77 | PTGS2 (0.53) | DPP4CYP2A6PTPRCCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-A | N- (pyridine -2- base) pyridine-sulfamide derivative and its purposes for disease treatment | 诺华股份有限公司 | 2019-04-16 | — | — | CN | disclosed |