Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | PI4KA | P42356 | 5/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.45 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | GMPS | P49915 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.43 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.43 |
| ▸ | GAPDH | P04406 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL226040 | 0.83 | ADORA2A (0.56) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1553826 | 0.79 | ADORA2A (0.46) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL120561 | 0.79 | ADORA3 (0.50) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL12987542 | 0.79 | ADORA2A (0.51) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL120550 | 0.78 | ADORA3 (0.51) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL28037447 | 0.77 | ADORA2A (0.54) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL30716566 | 0.76 | ADORA2A (0.53) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL28867974 | 0.76 | ADORA2A (0.55) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL29081873 | 0.75 | ADORA2A (0.54) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL29815498 | 0.75 | ADORA2A (0.52) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715637-A | Glucokinase activators and its application method | 百时美施贵宝公司 | 2019-05-03 | — | — | CN | disclosed |