SCHEMBL226040

SCHEMBL226040

C[C@@]1(n2cnc3c(N)ncnc32)O[C@H](CO)[C@@H](O)[C@@]1(C)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 3/20 0.56
SLC28A1 O00337 2/20 0.52
PI4KA P42356 3/20 0.52
PI4K2B Q8TCG2 3/20 0.52
PI4K2A Q9BTU6 3/20 0.52
PI4KB Q9UBF8 3/20 0.52
TAS1R3 Q7RTX0 2/20 0.49
TAS1R1 Q7RTX1 2/20 0.49
ADORA3 P0DMS8 5/20 0.49
GMPS P49915 1/20 0.49
DPP4 P27487 1/20 0.49
MEN1 O00255 1/20 0.49
MAP3K7 O43318 1/20 0.49
SLC28A2 O43868 1/20 0.49
GAPDH P04406 1/20 0.49
MAPK1 P28482 1/20 0.49
ADORA2B P29275 1/20 0.49
ADORA1 P30542 1/20 0.49
STAT6 P42226 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28867974 0.87 ADORA2A (0.55) ADORA2ASLC28A1PI4KAPI4K2BPI4K2A
SCHEMBL17460353 0.87 ADORA2A (0.42) ADORA2ASLC28A1PI4KAPI4K2BPI4K2A
SCHEMBL28037447 0.86 ADORA2A (0.54) ADORA2ASLC28A1PI4KAPI4K2BPI4K2A
SCHEMBL29081873 0.86 ADORA2A (0.54) ADORA2ASLC28A1PI4KAPI4K2BPI4K2A
SCHEMBL30716566 0.85 ADORA2A (0.53) ADORA2ASLC28A1PI4KAPI4K2BPI4K2A
SCHEMBL12987542 0.85 ADORA2A (0.51) ADORA2ASLC28A1PI4KAPI4K2BPI4K2A
SCHEMBL12987535 0.85 ADORA2A (0.45) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL6829141 0.85 ADORA2A (0.45) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL1300019 0.83 TAS1R3 (0.56) TAS1R3TAS1R1ADORA1SMN1; SMN2POLB
SCHEMBL28294010 0.83 ADORA2A (0.49) ADORA2ASLC28A1PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120064427-A Method and analysis system for detecting brain nucleic acid hydrolysate spatial distribution based on mass spectrum imaging 北京脑科学与类脑研究所 2025-05-30 CN claimed
EP-4384635-A1 IN SITU EPITRANSCRIPTOMIC PROFILING The Broad Institute Inc. (US) 2024-06-19 EP claimed
WO-2024086659-A2 COMPOSITION AND METHODS FOR DETECTING ADENINE MODIFICATIONS THE UNIVERSITY OF CHICAGO (US) 2024-04-25 WO claimed
CN-116298235-A Serum metabolism biomarker for diagnosing or monitoring breast cancer and screening method thereof 哈尔滨医科大学 2023-06-23 CN claimed
WO-2023023055-A1 COMPOSITIONS AND METHODS FOR OPTIMIZING TROPISM OF DELIVERY SYSTEMS FOR RNA RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-02-23 WO claimed
WO-2023018756-A1 IN SITU EPITRANSCRIPTOMIC PROFILING THE BROAD INSTITUTE, INC. (US) 2023-02-16 WO claimed
CN-114076805-B Method for enriching methylated adenosine in urine and application thereof 浙江大学 2022-07-26 CN claimed
WO-2022115822-A2 METHODS FOR FULL-LENGTH REVERSE TRANSCRIPTION PCR OF LONG RNAS CONTAINING MODIFIED RIBONUCLEOSIDES USING A THERMOSTABLE REVERSE TRANSCRIPTASE NORTHWESTERN UNIVERSITY (US) 2022-06-02 WO claimed
CN-114076805-A Method for enriching methylated adenosine in urine and application thereof 浙江大学 2022-02-22 CN claimed
CN-104804903-B Semiconductor cleaning agent with metal line 恩特格里斯公司 2018-10-30 CN claimed
CN-106399506-A Diagnostic methods for determining prognosis of non-small cell lung cancer 雅培分子公司 2017-02-15 CN claimed
EP-2755986-A1 ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF Moderna Therapeutics, Inc. (US) 2014-07-23 EP claimed
WO-2013039857-A1 ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF modeRNA Therapeutics (US) 2013-03-21 WO claimed
WO-2001085220-A1 LABELED NUCLEOSIDES AND METHOD FOR THEIR PREPARATION RNA-TEC N.V. (BE) 2001-11-15 WO claimed
US-20260146040-A1 USE OF CASEINOLYTIC PROTEASE P FUNCTION AS A BIOMARKER OF DRUG RESPONSE TO IMIPRIDONE-LIKE AGENTS Madera Therapeutics, LLC (US) 2026-05-28 US disclosed
US-12630527-B2 Broad spectrum anti-cancer compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-19 US disclosed
US-20260078415-A1 Differential Knockout of an Allele of a Heterozygous Elane Gene EMENDOBIO INC (US) 2026-03-19 US disclosed
EP-0708781-A1 A 3 ADENOSINE RECEPTOR AGONISTS THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) 1996-05-01 EP disclosed
EP-0269574-A2 Novel adenosine derivatives and pharmaceutical compositions containing them as an active ingredient NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) 1988-06-01 EP disclosed
EP-0238672-A1 PROCESS FOR DEOXIDIZING ALCOHOL Yamasa Shoyu Kabushiki Kaisha (JP) 1987-09-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630527-B2 Broad spectrum anti-cancer compounds YTHDF3, YTHDF1, YTHDF2 ADORA2A 2387/4885SLC28A1 1430/4885PI4KA 1587/4885
US-20260146040-A1 USE OF CASEINOLYTIC PROTEASE P FUNCTION AS A BIOMARKER OF DRUG RESPONSE TO IMIPRIDONE-LIKE AGENTS CTRB1, CTRB2, CPN1 ADORA2A 4503/4885SLC28A1 3074/4885PI4KA 3746/4885
US-20260078415-A1 Differential Knockout of an Allele of a Heterozygous Elane Gene ELANE, ENDOD1, UPF1 ADORA2A 4101/4885SLC28A1 1216/4885PI4KA 3355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.