Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.33 |
| ▸ | ENO1 | P06733 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28129907 | 0.86 | ENO1 (0.33) | ALDH1A1HSD11B1FKBP1AENO1KMT2A | |
| SCHEMBL27842168 | 0.86 | ENO1 (0.33) | ALDH1A1HSD11B1FKBP1AENO1KMT2A | |
| SCHEMBL27841989 | 0.86 | ENO1 (0.33) | ALDH1A1HSD11B1FKBP1AENO1KMT2A | |
| SCHEMBL27737962 | 0.86 | ENO1 (0.33) | ALDH1A1HSD11B1FKBP1AENO1KMT2A | |
| SCHEMBL27655729 | 0.86 | ALDH1A1 (0.34) | ALDH1A1HSD11B1FKBP1AENO1KMT2A | |
| SCHEMBL27377906 | 0.86 | ENO1 (0.33) | ALDH1A1HSD11B1FKBP1AENO1KMT2A | |
| SCHEMBL27757343 | 0.85 | ALDH1A1 (0.34) | ALDH1A1HSD11B1FKBP1AENO1HMGCR | |
| SCHEMBL27655719 | 0.85 | ALDH1A1 (0.34) | ALDH1A1HSD11B1FKBP1AENO1HMGCR | |
| SCHEMBL27737960 | 0.85 | ALDH1A1 (0.33) | ALDH1A1HSD11B1FKBP1AENO1KMT2A | |
| SCHEMBL27856093 | 0.85 | ALDH1A1 (0.33) | ALDH1A1HSD11B1FKBP1AENO1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776522-A | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2019-05-21 | — | — | CN | disclosed |