Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 3/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14308045 | 0.89 | HRH3 (0.47) | NOS3NOS1NOS2QPCTQPCTL | |
| SCHEMBL28294114 | 0.88 | QPCT (0.56) | CDK8FGFR2FGFR3FGFR1QPCT | |
| SCHEMBL1050653 | 0.82 | MAPT (0.47) | QPCTDPP4KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3632899 | 0.80 | MAPT (0.46) | QPCTDPP4KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7220537 | 0.80 | MAPT (0.46) | QPCTDPP4KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL32671448 | 0.80 | MAPT (0.46) | QPCTDPP4KDM4EALDH1A1MAPT | |
| SCHEMBL6008269 | 0.80 | MAPT (0.50) | QPCTQPCTLKDM4EALDH1A1MAPT | |
| SCHEMBL31143361 | 0.80 | MAPT (0.50) | QPCTQPCTLKDM4EALDH1A1MAPT | |
| SCHEMBL22418755 | 0.79 | QPCT (0.47) | FGFR1QPCTQPCTLDPP4KDM4E | |
| SCHEMBL2457365 | 0.79 | QPCT (0.50) | FGFR1QPCTQPCTLDPP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866543-B | A method of benzimidazole compound is catalyzed and synthesized under microwave radiation in water phase | 福建医科大学 | 2019-05-14 | — | — | CN | disclosed |