SCHEMBL28294419

SCHEMBL28294419

CCC[Ru]c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.38
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
PSIP1 O75475 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
PCSK9 Q8NBP7 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
LTA4H P09960 1/20 0.31
LMNA P02545 3/20 0.31
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
PTGS2 P35354 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL967556 0.61 ALDH1A1 (0.64) TP53HPGDSMN1; SMN2L3MBTL1KDM4E
SCHEMBL28024428 0.61 TP53 (0.55) TP53HPGDSMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL25312750 0.60 ALDH1A1 (0.40) HPGDSMN1; SMN2CES1KDM4EALDH1A1
Bromide SCHEMBL9265148 0.59 TP53 (0.52) TP53HPGDSMN1; SMN2L3MBTL1ALDH1A1
Toluene SCHEMBL991792 0.59 ACHE (0.73) TP53HPGDPSIP1CES2CES1
Biphenyl SCHEMBL22500791 0.59 ALDH1A1 (0.60) TP53HPGDSMN1; SMN2L3MBTL1KDM4E
Biphenyl SCHEMBL4606121 0.59 ALDH1A1 (0.60) TP53HPGDSMN1; SMN2L3MBTL1KDM4E
Biphenyl SCHEMBL7043290 0.59 ALDH1A1 (0.60) TP53HPGDSMN1; SMN2L3MBTL1KDM4E
Ethylbenzene SCHEMBL8160535 0.59
Bromobenzene SCHEMBL8009691 0.57 ALDH1A1 (0.69) TP53HPGDL3MBTL1PSIP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109762018-A A kind of preparation method of the phosphorus nitrence compound of ruthenium catalysis 大连理工大学 2019-05-17 CN claimed