Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4463757 | 0.84 | HDAC1 (0.58) | MEN1KMT2ASMN1; SMN2HDAC1POLB | |
| SCHEMBL28605755 | 0.83 | POLB (0.54) | MEN1KMT2ASMN1; SMN2HDAC1POLB | |
| SCHEMBL28610788 | 0.80 | GAA (0.56) | SMN1; SMN2POLBGAAMAPTRAB9A | |
| SCHEMBL28604661 | 0.80 | ALDH1A1 (0.61) | MEN1KMT2ASMN1; SMN2GAAMAPT | |
| SCHEMBL14438185 | 0.77 | POLB (0.81) | MEN1KMT2ASMN1; SMN2HDAC1POLB | |
| SCHEMBL46184 | 0.76 | MEN1 (0.71) | MEN1KMT2ASMN1; SMN2HDAC1POLB | |
| SCHEMBL4476444 | 0.74 | RAB9A (0.60) | MEN1KMT2ASMN1; SMN2HDAC1POLB | |
| SCHEMBL3288511 | 0.73 | RAB9A (0.68) | MEN1KMT2ASMN1; SMN2HDAC1POLB | |
| SCHEMBL4468028 | 0.73 | SMN1; SMN2 (0.43) | MEN1KMT2ASMN1; SMN2HDAC1MAPT | |
| SCHEMBL1041220 | 0.73 | RAB9A (0.64) | MEN1KMT2ASMN1; SMN2HDAC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109758442-B | Application of diaryl hydrazide compound in preparation of anti-influenza virus medicine | 武汉大学 | 2021-08-17 | — | — | CN | claimed |
| CN-109758442-A | Diaryl hydrazide kind compound is preparing the application in anti-influenza virus medicament | 武汉大学 | 2019-05-17 | — | — | CN | claimed |
| CN-109758442-B | Application of diaryl hydrazide compound in preparation of anti-influenza virus medicine | 武汉大学 | 2021-08-17 | — | — | CN | disclosed |
| CN-109758442-A | Diaryl hydrazide kind compound is preparing the application in anti-influenza virus medicament | 武汉大学 | 2019-05-17 | — | — | CN | disclosed |